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Advice for Irritable Bowel Syndrome

Irritable Bowel Syndrome or IBS is a common condition that affects the digestive system. The symptoms vary from stomach cramps, bloating, constipation and diarrhoea. The severity of these symptoms will vary from person to person. A typical episode of IBS can last for just a few days. For others, these episodes can be prolonged-lasting up to a few months at a time. Experiencing bouts of IBS is often linked with times of stress, or from eating certain trigger foods. Sadly, Irritable Bowel Syndrome is a life-long condition, although symptoms have been known to improve over a number of years.

IBS cannot be cured, however, there are a number of lifestyle choices that will help to manage the condition effectively. These include; identifying and avoiding food/drink triggers, increasing the amount of fibre in your diet, regular exercise and avoiding stress where possible.

Irritable Bowel Syndrome is not uncommon. The condition is estimated to affect up to one in five people at some point in their life. It typically develops between the ages of 20 and 30 and around twice as many women are affected as men.

Suffering from Irritable Bowel Syndrome can significantly impact a person’s day-to-day life, which in turn can have a psychological impact. This can easily result in many IBS sufferers experiencing associated feelings of depression or anxiety. If you believe you have IBS, it is important to go and see your GP for a diagnosis.

Diagnosis

Currently, there are no specific clinical tests that can identify IBS, as it does not cause any discernible abnormalities within the digestive system. In the majority of cases, a diagnosis will be based on the presenting symptoms. Your GP will usually consider assessing a patient for IBS If they have experienced abdominal pain/bloating or a change in their bowel habits for a period of six months or longer.

A diagnosis of Irritable Bowel Syndrome will be then considered if the stomach pain/discomfort is relieved by emptying the bowel or whether this pain is associated with the need to visit the toilet more frequently. To be able to perform an informed diagnosis, the criteria above will need to be accompanied by two or more of the following symptoms:

  • A change in the consistency of the stools
  • Bloating, hardness or tension in the abdominal area
  • A change in how stools are passed (straining/urgency/not feeling fully empty)
  • The passing of mucus from the anus

Most cases of Irritable Bowel Syndrome can be diagnosed on the symptoms alone. However, occasionally additional tests may be required to check for other possible causes and underlying conditions. For example; a blood test may be required to rule out certain conditions that present with similar symptoms, such as coeliac disease. A stool sample may also be requested to test for calprotectin, which is a substance produced by the gut when inflamed. The presence of calprotectin may suggest Inflammatory Bowel Disease (IBD) instead of Irritable Bowel Syndrome (IBS).

In a small number of cases, additional testing may be required if a patient presents with certain ‘red flag’ symptoms. These are symptoms that could potentially indicate the presence of a more serious condition, such as cancer. Red flag symptoms include:

  • Unexplained weight loss
  • Rectal bleeding
  • A lump of swelling in the stomach or anal passage

If you are over 60 years old or there is a family history of bowel or ovarian cancer, further testing may be recommended to rule out more serious conditions. In these cases, a colonoscopy will usually be performed to check for any abnormalities in the gut.

The symptoms of Irritable Bowel Syndrome are usually exacerbated by eating food. For most people, a flare-up will typically last a few days. After which, the symptoms will either improve dramatically or disappear altogether. In a lot of cases, IBS is usually triggered by recently consumed food or drink. In other cases, an episode can be brought upon by psychological factors, such as stress.

The most common symptoms associated with Irritable Bowel Syndrome are:

  • Abdominal pain
  • Cramping
  • Constipation
  • Diarrhoea
  • Bloating and swelling of the stomach
  • Excessive flatulence
  • Experiencing an urgent need to empty the bowel
  • Not feeling fully emptied after going to the toilet
  • Passing mucus from the anus

Other associated symptoms that are inherently linked with Irritable Bowel Syndrome include:

  • Lethargy
  • Nausea
  • Backache
  • Bladder problems (such as a frequent need to pass water at night or an inability to fully empty the bladder)
  • Dyspareunia (pain experienced during sexual intercourse)
  • Incontinence

The exact cause of IBS is not fully understood, but it is believed to result from a combination of factors that affect the digestive system. These factors can be categorized into several key areas:

Gastrointestinal Motility Issues

Abnormal Peristalsis: IBS may involve abnormal movements of the muscles in the intestinal walls, leading to either faster or slower transit times.
Spasms: The intestines can experience spasms, causing pain and irregular bowel movements.

Visceral Hypersensitivity

Increased Sensitivity: People with IBS often have an increased sensitivity to pain in the digestive tract, known as visceral hypersensitivity. Normal digestive activities may be perceived as painful.

Brain-Gut Interaction

Communication Problems: The brain and gut communicate through a network of nerves and biochemical signals. Disruptions in this communication can affect bowel function.
Stress Response: Stress and anxiety can alter the brain-gut interaction, exacerbating IBS symptoms.

Post-Infectious IBS

Gastrointestinal Infections: Some people develop IBS after a severe gastrointestinal infection, such as gastroenteritis. The infection can lead to changes in the gut flora and immune response.
Inflammation: Post-infectious inflammation can lead to ongoing symptoms of IBS.

Microbiome Imbalance

Gut Flora: An imbalance in the gut microbiome, the community of bacteria in the intestines, can contribute to IBS. Changes in the types and numbers of bacteria can affect digestion and immunity.
Small Intestinal Bacterial Overgrowth (SIBO): An overgrowth of bacteria in the small intestine can cause symptoms similar to IBS.

Food Sensitivities and Intolerances

Dietary Triggers: Certain foods can trigger IBS symptoms. Common triggers include dairy products, gluten, fatty foods, and high FODMAP foods (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols).
Food Intolerances: Some individuals may have specific intolerances to certain carbohydrates or other components in food.

Genetic Factors

Family History: IBS tends to run in families, suggesting a genetic component. However, specific genetic markers have not been definitively identified.
Inherited Traits: Genetics may influence gut motility, pain sensitivity, and other factors.

Psychological Factors

Mental Health: Conditions like anxiety, depression, and other psychological disorders are more common in people with IBS. These conditions can influence IBS symptoms.
Psychosocial Stressors: Life stressors and emotional disturbances can trigger or worsen IBS symptoms.

Hormonal Factors

Gender Differences: IBS is more common in women, suggesting a hormonal component. Symptoms often worsen around menstruation, indicating a potential link with reproductive hormones.

Immune System Abnormalities

Immune Response: Some research suggests that IBS may involve an abnormal immune response in the gut. Low-grade inflammation and immune system activation can affect gut function.

Understanding that IBS is a multifactorial condition helps tailor treatment approaches to address the various underlying causes and triggers. Management often involves a combination of dietary changes, stress reduction, and medication to alleviate symptoms. Working closely with a healthcare provider can help identify and manage individual triggers and contributing factors.

Treatment of IBS focuses on relieving symptoms so that you can live as symptom-free as possible. Mild symptoms can often be controlled by managing stress and by making changes in your diet and lifestyle. Try to:

  • Avoid foods that trigger your symptoms
  • Eat high-fiber foods
  • Drink plenty of fluids
  • Exercise regularly
  • Get enough sleep

Antispasmodics are medicines that work by relaxing the muscles in the digestive system. These medicines are the most commonly used IBS treatments and help to ease cramping and bloating. They are generally well tolerated with associated side-effects being quite rare. Examples of antispasmodics include; Mebeverine (Colofac), Alverine Citrate and therapeutic Peppermint Oil (Colpermin). At Pharmacinta, we provide Mebeverine Tablets to manage your symptoms.

There are a variety of different treatments available to help treat Irritable Bowel Syndrome.

Laxatives

Bulk-forming laxatives are generally recommended for patients who experience IBS-related constipation. They work by softening stools, which makes them easier to pass. Whilst taking bulk-forming laxatives it is important to drink plenty of fluid this will stop the laxative from creating a blockage in the digestive system. Possible side-effects can include; bloating and flatulence. However, if taken appropriately these side-effects are minimised. An example of a bulk-forming laxative is; Ispaghula Husk (Fybogel).

Antimotility Medicines

Antimotility medicines work by reducing the contractions of the muscles in the bowel. This has the effect of slowing down the speed at which food passes through the digestive system. This process allows extra time for the passing stool to solidify. Associated side effects include stomach cramps, bloating, drowsiness, dizziness and rashes. An example of an antimotility medicine is; Loperamide (Imodium).

Antidepressants

There are two types of antidepressants used to help treat IBS. The first being; Tricyclic Antidepressants (TCAs) and the second; Selective Serotonin Reuptake Inhibitors (SSRIs).

TCAs are generally recommended where antispasmodics have been found ineffective. TCAs work by interrupting the signals sent between the nerves and the digestive system. The body needs to first get used to TCAs before the effects are felt, which usually takes between 3-4 weeks. The most common side-effects associated with TCAs are; dry mouth, constipation, drowsiness and blurred vision. However, these side-effects usually improve after the first few days of starting treatment. An example of a TCA is amitriptyline.

Alternatively, SSRI can be used to help treat Irritable Bowel Syndrome. The most common side-effects include; dizziness, diarrhoea and blurred vision. Examples of SSRIs include; Citalopram, Fluoxetine and Paroxetine.

Dietary Approaches

Low FODMAP Diet

Description: A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.
Effectiveness: Can reduce symptoms like bloating, gas, and abdominal pain.
Foods to Avoid: High-FODMAP foods include certain fruits (apples, pears), vegetables (onions, garlic), dairy products, and sweeteners.

High-Fiber Diet

Description: Increasing dietary fiber can help regulate bowel movements.
Sources: Whole grains, fruits, vegetables, and legumes.
Effectiveness: Beneficial for constipation-predominant IBS (IBS-C).

Elimination Diets

Description: Removing potential food triggers from the diet and gradually reintroducing them.
Common Triggers: Gluten, dairy, caffeine, and fatty foods.
Effectiveness: Helps identify specific food sensitivities.

Herbal and Natural Supplements

Peppermint Oil

Description: Has antispasmodic properties that can help relax the muscles of the gastrointestinal tract.
Effectiveness: Reduces abdominal pain and bloating.
Form: Enteric-coated capsules to avoid heartburn.

Probiotics

Description: Beneficial bacteria that help balance the gut microbiota.
Strains: Bifidobacterium and Lactobacillus species.
Effectiveness: Can improve symptoms like bloating and irregular bowel movements.

Mind-Body Therapies

Cognitive Behavioral Therapy (CBT)

Description: A type of therapy that helps change negative thought patterns and behaviors.
Effectiveness: Reduces symptom severity and improves quality of life.
Sessions: Typically involves 8-12 sessions with a trained therapist.

Yoga and Meditation

Description: Practices that promote relaxation and stress management.
Effectiveness: Can improve overall well-being and reduce symptoms of IBS.
Types: Hatha yoga, mindfulness meditation.

Acupuncture

Description: An ancient Chinese practice involving the insertion of thin needles into specific points on the body.
Effectiveness: May help reduce abdominal pain and improve bowel function.
Sessions: Typically requires multiple sessions for noticeable benefits.

Lifestyle Modifications

Regular Exercise

Description: Physical activity can help regulate bowel movements and reduce stress.
Types: Walking, swimming, cycling, or any preferred exercise.
Effectiveness: Consistent exercise can improve overall IBS symptoms.

Stress Management

Description: Reducing stress can alleviate IBS symptoms.
Techniques: Deep breathing exercises, progressive muscle relaxation, and time management strategies.
Effectiveness: Lowering stress levels can have a positive impact on IBS.

Adequate Hydration

Description: Drinking plenty of water can help prevent constipation.
Effectiveness: Staying hydrated supports digestive health.

Frequently Asked Questions

IBS is a common gastrointestinal disorder characterized by symptoms such as abdominal pain, bloating, gas, and altered bowel habits, including diarrhea and constipation.

Diagnosis typically involves evaluating symptoms, taking a medical history, conducting a physical exam, and possibly performing tests such as blood tests, stool tests, or colonoscopy to rule out other conditions.

No, IBS is a functional disorder without visible intestinal damage, while IBD involves inflammation and damage to the digestive tract.

The types include IBS with constipation, IBS with diarrhea, IBS with mixed bowel habits, and unsubtyped IBS.

Yes, certain foods can trigger symptoms, with common triggers including high FODMAP foods, fatty foods, dairy products, caffeine, and gluten.

A low FODMAP diet reduces the intake of specific carbohydrates that are poorly absorbed, which can help alleviate symptoms for many people with IBS.

Treatment options may include antispasmodics, laxatives, antidiarrheal medications, antidepressants, and newer medications designed for specific IBS types.

Yes, techniques such as cognitive behavioral therapy, hypnotherapy, mindfulness, and regular exercise can significantly reduce IBS symptoms.

IBS can be chronic, but symptoms often vary over time and can be managed effectively through lifestyle changes and medical treatments.

Probiotics can be beneficial for some individuals by helping to balance gut bacteria, with specific strains often recommended.

Incorporating regular exercise, staying hydrated, following a balanced diet, managing stress, and ensuring good sleep hygiene can help manage symptoms.

Alternative treatments such as peppermint oil, ginger, acupuncture, yoga, and biofeedback may provide relief for some people.

While IBS itself does not cause serious conditions like cancer, it can impact quality of life and is sometimes associated with other health issues.

Keeping a food diary and symptom log can help identify triggers and patterns, making it easier to manage IBS.

IBS is more commonly diagnosed in women, with hormonal changes possibly influencing symptom severity.

Yes, IBS can affect individuals of any age, including children, and the symptoms and management strategies are similar to those for adults.

If IBS is suspected, it's important to consult a healthcare provider for proper diagnosis and to discuss an effective management plan.

There is currently no cure for IBS, but many individuals successfully manage their symptoms through dietary changes, medications, and lifestyle modifications.

Mebeverine is a medication used to relieve symptoms of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders by reducing muscle spasms in the gut.

Mebeverine acts as a smooth muscle relaxant, helping to ease abdominal pain and cramping by relaxing the muscles in the gut.

Mebeverine is primarily used to treat IBS and other conditions characterized by gastrointestinal spasms and discomfort.

Mebeverine is generally considered safe for long-term use, but it’s important to regularly consult a healthcare provider to monitor ongoing symptoms.

Mebeverine has few known interactions, but it’s essential to inform your healthcare provider about all medications and supplements you are taking.

While Mebeverine is safe for many individuals, those with specific medical conditions or allergies should consult a healthcare provider before use.

Many individuals may start to feel relief within a few days, but it can take longer for some. Consistent use is often necessary for optimal results.

There are no specific dietary restrictions while taking Mebeverine, but maintaining a balanced diet and avoiding known IBS triggers can help manage symptoms.

Mebeverine is not known to cause dependency, as it does not affect the central nervous system.

While Mebeverine is effective for many individuals with IBS, responses can vary. Some may require additional or alternative treatments.

Mebeverine can help alleviate abdominal pain and cramping associated with both diarrhea-predominant and constipation-predominant IBS.

In some countries, Mebeverine may be available over the counter, but it is often prescribed by healthcare providers for IBS management.

Mebeverine is exactly the same as Colofac as it has the same active ingredient — Colofac is just the same drug manufactured under a different name (brand). Same goes for Duspatalin (US brand) — it’s just another name for the same drug. Buscopan is slightly different and is made up hyoscine butylbromide (or scopolamine butylbromide) and is used to treat abdominal pain and bladder spasms. As it’s also an antispasmodic, it is not recommended that you take it at the same time as Mebeverine.

Mebeverine is an antispasmodic which means that it helps to relax the smooth muscle in the gut and control the cramps and painful stomach spasms associated with IBS.

There is little information regarding the use of Mebeverine during pregnancy. Speak to your GP before taking it. It is important to make your GP aware of any gastrointestinal symptoms during your pregnancy.

Mebeverine is used to treat spasms caused by IBS or other intestinal conditions. In fact, it is not recommended for use in case the patient is suffering from constipation or an inactive gut as it can further aggravate the problem.

No, Mebeverine does not necessarily cause weight gain. It is the underlying problem that can lead to weight gain. For instance, patients suffering from IBS may suffer from dysbiosis of gut microbiota, which can lead to gut distention and water retention. This may cause the patient to feel slightly bloated and overweight. However, this is not directly related to the intake of Mebeverine.

Mebeverine is an effective drug for the treatment of colicky abdominal pain, cramps, and persistent diarrhea. Further, these symptoms may or may not be accompanied by flatulence. Some of these symptoms are also a direct fall out of IBS and should be treated accordingly with the help of Mebeverine.

The medication is prescribed by the doctor for a particular duration depending on the severity of the symptoms. So, it is subjective and would differ from person to person. It is ideally eaten 20 minutes before meals and starts its work in reducing the symptoms or discomfort after an hour so take the medication accordingly.

Mebeverine is an antispasmodic drug that reduces the discomfort and pain caused by muscular cramps and spasms. It is a prescription medication given to patients suffering from IBS or Colitis. It can alleviate symptoms of bloating or distention that is brought about by IBS.

This depends a lot on whether you take it in tablet or capsule form. The standard tablets, taken thrice a day, stay in the system for 6-8 hours whereas the slow release capsules stay in the system longer. Depending on the severity of your symptoms, space them out evenly throughout the day.

You cannot take Mebeverine and Buscopan simultaneously as they tend to have the same properties and are used to treat the same conditions. Both are used to remedy or treat spasms and muscular cramps and so both can be used

Mebeverine is not usually recommended to be taken during pregnancy. While there is no information available to say whether it is safe or not, most doctors exercise caution and do not prescribe it. If you are pregnant or trying to get pregnant and suffer from IBS, speak to your doctor about other alternative drugs that can be taken.

Mebeverine is a common prescription drug that is given for the treatment of spasms and muscular contractions caused or bought on by IBS. It is highly effective as a long-term course of treatment and can be given to patients who chronically suffer from IBS.

Mebeverine is an antispasmodic drug and is not addictive. Even in the eventuality that you take the drug over a long period of time, it is highly unlikely to cause an addiction. However, if you do feel uncomfortable after having taken an excess of the medicine, do speak to your medical practitioner who can guide you.

Consult your doctor before taking alverine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of alverine in these situations has not been fully established.

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not take a double dose to make up for a missed one.

Store alverine in a cool, dry place away from direct sunlight and out of reach of children.

Alverine can cause dizziness in some individuals. If you experience dizziness or other side effects that impair your ability to concentrate, avoid driving or operating heavy machinery.

Many people experience relief from symptoms within a short period after starting alverine. However, individual responses may vary.

Alverine is generally not recommended for children under 12 years old unless specifically advised by a healthcare provider.