The usual dose of Betnesol-N is 2 to 3 drops into the ear 3 to 4 times daily. You should continue to use the spray until 2 days after the symptoms have disappeared. If your condition worsens or doesn’t improve after 7 days, stop using the spray and speak to your GP for advice.

You should notice an improvement to symptoms relatively soon after using Betnesol-N spray. If there is no improvement after 7 days of use, you should stop the course and consult your GP.

Follow the instructions below to ensure appropriate use of this medication:

• Before using, ensure the bottle has not been tampered with - the seal on the bottle should not be broken before first use
• Wash and dry your hands before applying treatment
• Shake the bottle well before using
• Pump several times until you get a measured spray
• One measured spray equals one dose
• Tilt your head (the affected ear should be facing upwards)
• Place the nozzle into the affected ear and spray one dose
• Your head should remain tilted for a few minutes (1-2) to allow the drops to soak in
• Repeat this process for the other ear if needed
• Repeat this process 3 times every day, until the inflammation is starting to clear
• The spray should be disposed of four weeks after first opening it, because after this time the spray may be contaminated.

In the event you miss a dose, it is safe to apply the missed dose as soon as possible. However, if enough time has passed that you should be applying your next dose instead, simply skip the missed dose and resume your typical application schedule.

Always use this medication exactly as your clinician has told you. Check with our clinical team or your GP or pharmacist if you are not sure.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

The most widely reported side effects of Otomize spray includes:

• Red, irritated or itchy skin
• Burning sensation
• Stinging feeling

For full information on side effects and correct use, see the patient information leaflet. If any side effects concern you, or you are experiencing any of the side effects mentioned in the patient information leaflet whilst taking this medication, please contact our clinical team or speak to your GP.

If Betnesol-N is used for a long time, it may cause adrenal suppression, which means it can prevent your body from producing its own natural steroids. If you stop using it after long-term use, you could experience some of the following:

• Itchy and painful skin
• Cold/flu like symptoms such as a fever, a runny nose, muscle and joint pain
• Low blood pressure
• Weight loss

You should not use this medication if you have:

• A grommet fitted
• A perforated tympanic membrane

Inform our clinical team before using this treatment if:

• You have tuberculosis
• You suffer from any other ear (including hearing) conditions.
• You are pregnant or planning to become pregnant - there may be a small risk to the foetus
• You are breastfeeding

This medication should not be used for a prolonged time, as long-term use of corticosteroids can have adverse effects. Excessive use of this medication, especially on open wounds in the ears, can cause hearing issues. It should not be used more than three times in a year. If you find yourself suffering from regular ear infections, you should consult your GP as there may be an underlying cause.

Get emergency medical help if you have signs of an allergic reaction to this medication. These include:

• Hives
• Dizziness
• Fast or pounding heartbeats
• Wheezing
• Difficult breathing
• Swelling of your face, lips, tongue, or throat.

It is important that you let us know which prescription, over-the-counter medicines and recreational drugs you are currently taking. You must also tell us about any other medical conditions that you currently have (or had in the past). This will help us ensure the prescribed medication is safe and appropriate for you to take.

For full information on warnings, medication interactions and contraindications, refer to the Patient Information Leaflet. Please read all packaging and the Patient Information Leaflet before taking any new medicine and inform our clinical team or your GP of medicines you are taking or intend to take.