Tranexamic acid dosage for the treatment of heavy menstrual bleeding typically involves taking Two 500 mg tablets three times daily. The treatment usually begins on the first day of menstruation and continues for up to four days.

To take tranexamic acid, swallow the tablets whole with water, and it can be taken with or without food. It is important to follow the healthcare provider's instructions regarding dosage and duration of treatment to ensure safety and effectiveness.

If a dose is missed, it should be taken as soon as remembered, unless it's nearly time for the next dose, in which case, the missed dose should be skipped. Patients should not double the dose to make up for a missed one. Regular follow-up with a healthcare provider is recommended to monitor the medication's effectiveness and any potential side effects.

Always use this medication exactly as your clinician has told you. Check with our clinical team or your GP or pharmacist if you are not sure.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Tranexamic acid is generally well-tolerated, but like any medication, it can cause side effects. Here are the detailed side effects associated with tranexamic acid:

Common Side Effects

Gastrointestinal Issues:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain or discomfort

Headache: Some users may experience headaches, which can range from mild to moderate.

Dizziness or Lightheadedness: A few individuals may feel dizzy or lightheaded, particularly when standing up quickly.

Serious Side Effects

Thromboembolic Events: There is a risk of blood clots forming in veins or arteries, which can lead to serious complications such as deep vein thrombosis (DVT), pulmonary embolism (PE), or stroke. Individuals with a history of thromboembolic disorders should be monitored closely.

Visual Disturbances: In rare cases, some users may experience visual disturbances, such as blurred vision or changes in color perception, particularly if prescribed high doses.

Kidney Issues: High doses or prolonged use may affect kidney function. Symptoms of kidney problems can include decreased urine output or swelling in the legs and ankles.

Other Considerations

Liver Function: Caution is advised in patients with liver dysfunction since the drug is metabolized by the liver.

Hormonal Considerations: Tranexamic acid may interact with other medications that affect coagulation; therefore, comprehensive disclosure of all current medications and health conditions to the healthcare provider is essential.

Monitoring

Individuals taking tranexamic acid are advised to have regular follow-ups with their healthcare provider to monitor for side effects, especially if they have risk factors for clotting disorders or other underlying health issues.

For full information on side effects and correct use, see the patient information leaflet. If any side effects concern you, or you are experiencing any of the side effects mentioned in the patient information leaflet whilst taking this medication, please contact our clinical team or speak to your GP.

When using tranexamic acid, it is important to consider the following cautions and warnings:

Cautions:

Thromboembolic Risk: Patients with a history of thromboembolic disorders, such as deep vein thrombosis (DVT) or pulmonary embolism (PE), should use tranexamic acid with caution, as it may increase the risk of further clotting events.

Renal Impairment: Individuals with kidney dysfunction may require dosage adjustments and closer monitoring, as the drug is primarily eliminated by the kidneys.

Liver Dysfunction: Caution is advised for patients with liver impairment, as the metabolism of tranexamic acid can be affected.

Hormonal Contraceptives: Women taking hormonal contraceptives or hormone replacement therapy should inform their healthcare provider, as these medications may increase the risk of thrombosis when combined with tranexamic acid.

Visual Disturbances: If any visual changes occur, the medication should be discontinued immediately, and medical advice should be sought.

Warnings:

Monitor for Symptoms of Thrombosis: Patients should be vigilant for symptoms indicative of thromboembolic events, such as swelling or pain in the legs, sudden shortness of breath, or chest pain, and report these to a healthcare provider promptly.

Use of Anticoagulants: Caution should be exercised when tranexamic acid is used in conjunction with anticoagulants or other anti-platelet drugs, as this may alter coagulation profiles and increase the risk of thrombotic events.

Pregnancy and Breastfeeding: Pregnant or breastfeeding women should consult with their healthcare provider to weigh the benefits and risks of using tranexamic acid.

Method of Administration: Tranexamic acid should not be injected into the spinal canal, as this can lead to serious complications. It should be used only as directed.

Get emergency medical help if you have signs of an allergic reaction to this medication. These include:

• Hives
• Dizziness
• Fast or pounding heartbeats
• Wheezing
• Difficult breathing
• Swelling of your face, lips, tongue, or throat.

It is important that you let us know which prescription, over-the-counter medicines and recreational drugs you are currently taking. You must also tell us about any other medical conditions that you currently have (or had in the past). This will help us ensure the prescribed medication is safe and appropriate for you to take.

For full information on warnings, medication interactions and contraindications, refer to the Patient Information Leaflet. Please read all packaging and the Patient Information Leaflet before taking any new medicine and inform our clinical team or your GP of medicines you are taking or intend to take.