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Mebeverine is a medication used to relieve symptoms of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders. It belongs to the class of drugs known as antispasmodics. Mebeverine works by directly affecting the smooth muscle in the gastrointestinal tract, inhibiting calcium influx and blocking sodium channels. These actions help to reduce muscle contractions and spasms without impacting normal gut motility.
Mebeverine is considered effective in alleviating symptoms of irritable bowel syndrome (IBS) and other functional gastrointestinal disorders, particularly by reducing abdominal pain, cramps, and discomfort associated with muscle spasms, and it is generally well-tolerated with a low incidence of side effects.
For adults, the typical dose of mebeverine is 135 mg taken three times a day before meals. Swallow the tablets or capsules whole with water, without crushing or chewing them. Take the medication about 20 minutes before meals and try to maintain a consistent schedule each day. If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose; do not double up on doses. Continue taking mebeverine as prescribed, even if you start feeling better, and do not stop without consulting your doctor.
Always use this medication exactly as your clinician has told you. Check with our clinical team or your GP or pharmacist if you are not sure.
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Digestive Issues
Central Nervous System
Skin Reactions
General
Cardiovascular System
For full information on side effects and correct use, see the patient information leaflet. If any side effects concern you, or you are experiencing any of the side effects mentioned in the patient information leaflet whilst taking this medication, please contact our clinical team or speak to your GP.
Inform your doctor if you have any underlying health conditions, especially those affecting the heart, kidneys, or liver. Adjustments in dosage or monitoring may be necessary.
Consult your clinician before taking mebeverine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of mebeverine during pregnancy and lactation has not been fully established.
Mebeverine can cause dizziness in some individuals. If you experience dizziness or any other side effects that affect your ability to concentrate, avoid driving or operating heavy machinery.
There are no known interactions between mebeverine and alcohol. However, consuming alcohol can irritate the gastrointestinal tract and may worsen symptoms of irritable bowel syndrome (IBS).
Get emergency medical help if you have signs of an allergic reaction to this medication. These include:
It is important that you let us know which prescription, over-the-counter medicines and recreational drugs you are currently taking. You must also tell us about any other medical conditions that you currently have (or had in the past). This will help us ensure the prescribed medication is safe and appropriate for you to take.
For full information on warnings, medication interactions and contraindications, refer to the Patient Information Leaflet. Please read all packaging and the Patient Information Leaflet before taking any new medicine and inform our clinical team or your GP of medicines you are taking or intend to take.