Zidoval gel is an antibacterial medicine for bacterial vaginosis (BV) that kills the bacteria responsible for causing the infection. The gel, which contains metronidazole, is applied directly inside the vagina to kill the bacteria and treat the condition. This medicine is prescription only, and cannot be bought over the counter. Patients are advised to take the full course in order to clear the infection completely – otherwise it may recur.

Zidoval gel which contains Metronidazole kills bacteria by interfering with its DNA. It’s used to kill a particular strain of bacteria known as ‘anaerobic bacteria’, which doesn’t need oxygen to multiply. It is this type of bacteria that’s responsible for causing BV. Metronidazole topical gel should be used for five consecutive days in order to cure your infection. For best results, it’s a good idea to use metronidazole BV gel (Zidoval) at the same time every day. Stopping too early, before your BV treatment is finished, can lead to the infection coming back.

Zidoval gel is specifically for bacterial vaginosis. It should not be used to treat other types of vaginal infections, such as yeast infections or sexually transmitted infections. Misuse could lead to resistance or inadequate treatment.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Zidoval gel, which contains metronidazole as its active ingredient, is used primarily for the topical treatment of bacterial vaginosis. Here is a detailed overview of the potential side effects associated with Zidoval gel:

Local Reactions:

• Vaginal Irritation: Some users may experience irritation, burning, or discomfort in the vaginal area where the gel is applied.
• Itching: Itching in the vaginal area or external genitalia can occur.
• Dryness:The gel might cause dryness or a sensation of tightness in the vaginal area.

Allergic Reactions:

• Rash: A localized rash or hives can develop at the application site.
• Swelling: Swelling of the vaginal or external genital tissues may occur in some individuals.
• Severe Allergic Reactions: Rarely, severe allergic reactions such as angioedema (swelling of the face or throat) may occur, requiring immediate medical attention.

Systemic Effects (Less Common):

• Headache: Some users may experience headaches as a result of the gel, although this is less common compared to oral forms of metronidazole.
• Dizziness: A few individuals might feel lightheaded or dizzy.

Other Reactions:

• Discharge Changes: Some users may notice changes in vaginal discharge, including increased or altered consistency or color.
• Unpleasant Odor: In some cases, the gel may cause an unpleasant odor.

Rare Side Effects:

• Local Dermatitis: Rare cases of dermatitis or severe skin reactions at the application site may occur.
• Systemic Absorption: Although rare, significant systemic absorption of metronidazole can happen, leading to potential systemic side effects like nausea, vomiting, or abdominal pain.

For full information on side effects and correct use, see the patient information leaflet. If any side effects concern you, or you are experiencing any of the side effects mentioned in the patient information leaflet whilst taking this medication, please contact our clinical team or speak to your GP.

You should also speak to a medical professional before using Zidoval gel if:

• You are having your period
• You are having blood tests
• You have ever had any blood problems
• You think you may have vaginal thrush (candidiasis)

With any vaginal infection, it’s best to avoid sexual intercourse until the infection clears up – and while using Zidoval gel.